mAb-factory




HOME

CONTACT






NEWS




7/2020  - Texas A&M AgriLife licenses mAb-factory technology to improve their development of innovative antibiotic strategies

The Center for Phage Technology (CPT) at Texas A&M AgriLife is a world leader in advancing the application of phage to combat bacterial infections and will now use our ultra-large gene library and selection technologies.

12/2016  - Antibody discovery and engineering services provided by YUMAB

Human antibody discovery and antibody engineering services based on our antibody phage display technologies are now provided by our partner Yumab GmbH (www.yumab.com). Please contact Yumab. directly for the generation of therapeutic antibodies for your clinical pipeline.


12/2016  - Crystal structure of a human antibody from library HAL9

Erik Sundberg and Sandra Postel (University of Maryland) presented the X-ray crystal structure of a human immunglobulin Fab fragment binding to flagellar capping protein (FliD, UniProtKB: Q9K3C5) from Pseudomonas aeruginosa. The Fab fragment was derived by conversion from the original scFv antibody fragment isolated by phage display from the HAL9 naive human monoclonal antibody library in the framework of an academic reserach collaboration. FliD is responsible for the adhesion of the bacterium to mucin, which is the initial event in colonization by this organism of the airways of cystic fibrosis patients.


11/2016 - Therapeutic human antibody pipeline news

CALYPSO Biotech SA, Switzerland (www.calypsobiotech.com) reports the successful generation of Anti-MMP-9 (Matrix metalloprotease 9) antibodies for their therapeutic pipeline by using our technology platform for the selection of human monoclonal antibodies. MMP-9 is a promising target for the treatment of Inflammatory Bowel Disease.

Reference: Goffin L, Fagagnini S, Vicari A, Mamie C, Melhem H, Weder B, Lutz C, Lang S, Scharl M, Rogler G, Chvatchko Y, Hausmann M. Anti-MMP-9 Antibody: A Promising Therapeutic Strategy for Treatment of Inflammatory Bowel Disease Complications with Fibrosis. Inflamm Bowel Dis. 2016 Sep;22(9):2041-57. - Link to publication